Impacts of the preempt protocol on chronic migraine: an integrative review

Chronic migraine is an important cause of functional disability and quality life deficits, affecting 12% the world population. Therefore, more treatment alternatives that promote better pain control are needed. So, botulinum toxin type A presents itself as a therapeutic option for this purpose. This integrative review aimed to analyze functionality PREEMPT protocol applied chronic migraine, analyzing time control, frequency repetition possible subtypes benefit most from toxin. Data were collected National Library Medicine Lilacs databases, research concluded in July 2022. 31 articles found, which only 22 publications considered eligible compose study, those contemplated objectives selected. above. Botulinum effective, safe well-tolerated preventive profile patients with increasing patient's works control.